Ethicon’s Plus Sutures
Ethicon’s Plus Sutures

Ethicon’s Plus Sutures

Become the First and Only Sutures¥ with Antibacterial Protection recommended for use in NHS by NICE Medical Technologies guidance.1

Note: Image for illustrative purposes only
 

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We are inspired by the opportunity to work together to advance patient care

Working together, we can deliver innovative solutions to today's healthcare challenges to advance patient care and deliver clinical and economic value to healthcare systems throughout the world.

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“Plus Sutures are cost saving compared with non-triclosan absorbable sutures by an average of £13.62 per patient.* These savings are from reduced surgical site infections.”

NICE Medical Technologies Guidance | Published 28 June 2021

NICE Medical Technologies Guidance

“The report indicates that by preventing surgical site infections, using Plus Sutures results in potential environmental benefits to the NHS in England.”1

NICE Medical Technologies Guidance | Published 28 June 2021


NOTE: Prevention of surgical site infection by using Plus Sutures is not an approved product claim by Ethicon, and can therefore not be actively promoted.

NICE Medical Technologies Guidance

NICE Medical Technology Guidance:

Plus Sutures for Preventing Surgical Site Infection1

NOTE: Prevention of surgical site infection by using Plus Sutures is not an approved product claim by Ethicon, and can therefore not be actively promoted.

NICE Medical Technology Guidance:

ETHICON Plus Antibacterial Sutures

Plus Sutures – the only sutures with Triclosan available worldwide with antibacterial protection offered by IRGACARE®† MP (Triclosan).**2

ETHICON Plus Antibacterial Sutures
Plus Sutures Virtual Reality

Triclosan-coated Sutures

Triclosan-coated sutures have been shown in multiple meta-analyses to reduce the risk of SSIs by 28%3-5

Triclosan-coated Sutures

“Plus Sutures are cost-saving compared with non-Triclosan absorbable sutures by an average of £13.62 per patient.*
These savings are from reduced surgical site infections.”1

NICE Medical Technologies Guidance | Published 28 June 2021

NICE Medical Technologies Guidance

Global Health Authorities - Statements on Triclosan-coated Sutures

World Health Organization 20166

World Health Organization 20166

The panel suggests the use of Triclosan-coated sutures for reducing the risk of SSI, independent of the type of surgery (conditional recommendation, moderate quality of evidence).6

Centre for Disease Control and Prevention, 20177

Centre for Disease Control and Prevention, 20177

Consider the use of Triclosan-coated sutures for the prevention of SSI.7
NOTE: Prevention of surgical site infection by using Plus Sutures is not an approved product claim by Ethicon, and can therefore not be actively promoted.
 

American College of Surgeons/Surgical Infection Society, 2016  SSI-guidelines8

American College of Surgeons/Surgical Infection Society, 2016 
SSI-guidelines8

Triclosan antibacterial suture use is recommended for wound closure in clean and clean-contaminated abdominal cases when available.8

Local Health Authorities - Statements on Triclosan-coated Sutures: UK, Germany & European Network
 

NICE Guidelines Update 20199

NICE Guidelines Update 20199

When using sutures, consider antimicrobial Triclosan-coated sutures, especially for paediatric surgery, to reduce the risk of surgical site infection (2019).9

Commission for Hospital Hygiene and Infection Prevention 201810

Commission for Hospital Hygiene and Infection Prevention 201810

Antiseptically coated sutures only reduce the threat of infection where there are high baseline SSI rates, contamination class III and IV surgeries, and patients with multiple morbidities (Cat. II).10

European Network for Health Technology Assessment 201711

European Network for Health Technology Assessment 201711

A statistically significant benefit of Triclosan-coated sutures in reducing the risk of total incisional SSI was demonstrated in our SR/MA# based on moderate quality RCTs Data.11

Ethicon’s new patient pathway programmes

including care4today® recovery, a communication tool for the healthcare team to:
• Monitor patient and wound recovery remotely 
• Access to real world data in real time

Designed for ease of use for both HCPs and patients:
• Patients get questions by notifications
• HCPs may collect high quality data to support future patient outcomes
 

Ethicon’s new patient pathway programmes
prehead

We are inspired by the opportunity to work together to advance patient care

Working together, we can deliver innovative solutions to today's healthcare challenges to advance patient care and deliver clinical and economic value to healthcare systems throughout the world.

Contact Us

References

* By using Plus Sutures compared with non-triclosan absorbable sutures, likely to be conservative.

** There are no competitive Triclosan coated sutures that have both FDA clearance and CE Mark as of June 2020.

† A trademark of BASF .

# Systematic Review/Meta-Analysis.

§ Cost savings will vary by surgery type and baseline risk of surgical site infection

¥ As of August 2021

1. © NICE 2021. MEDICAL TECHNOLOGY GUIDANCE: PLUS SUTURES FOR PREVENTING SURGICAL SITE INFECTION. Available from: nice.org.uk/guidance/MTG59Accessed on: 28 June 2021. All rights reserved. Subject to Notice of rights. NICE guidance is prepared for the National Health Service in England. All NICE guidance is subject to regular review and may be updated or withdrawn. NICE accepts no responsibility for the use of its content in this product/publication

2. Ethicon, Market intelligence and internal knowledge (144092-200619)

3. de Jonge S, Atema J, Solomkin J and Boermeester M, Meta-Analysis and trial sequential analysis of triclosan-coated sutures for the prevention of surgical-site infection. 2017; BJS 104 e118-e133. (144091-200619)

4. Wang Z, Jiang C, Cao Y, Ding Y. Systematic review and meta-analysis of Triclosan-coated sutures for prevention of surgical-site infection. Br J Surgery 2013; 100:465-474. (144091-200619)

5. Edmiston C, Daoud F, Leaper D. Is there an evidence-based argument for embracing an antimicrobial (Triclosan)-coated suture technology to reduce the risk for surgical-site infections? A meta-analysis. Surgery 2013; 154: 89-100. (144091-200619)

6. World Health Organization. Global guidelines for the prevention of surgical site infection.https://apps.who.int/iris/bitstream/handle/10665/250680/9789241549882-eng.pdf?sequence=8. Published November 2016. Accessed April 3, 2020. 

7. Berrios-Torres S, Umscheid C, Bratzler D, et al. Centers for disease control and prevention guideline for the prevention of surgical site infection, 2017. JAMA Surg. 2017;152(8):784-791. 

8. Ban K, Minei J, Laronga C, et al. American college of surgeons and surgical infection society: surgical site infection guidelines, 2016 update. J Am Coll Surg. 2017; 224(1):59-74. 

9. NICE Guideline Updates Team (UK). Surgical site infection: prevention and treatment. NICE website. https://www.nice.org.uk/guidance/ng125/chapter/Recommendations#closuremethods. Accessed July 20, 2021.

10. Prevention of postoperative wound infections. Recommendation of the Committee for Hospital Hygiene and Infection Prevention (KRINKO) at the Robert Koch Institute. Bundesgesundheitsbl. 2018;61(4):448-473.

11. EUnetHTA, Rapid assessment of JA3 WP4 on “Antibacterial-Coated Sutures Versus Non-Antibacterial-Coated Sutures For The Prevention Of Abdominal, Superficial And Deep Incisional, Surgical Site Infection (SSI) March 2017, V1.4.  

RESOURCES FOR PAGE
Ethicon, Approved EMEA/UK NICE External Summary of NICE PLUS MTG:  180931-210623.  Expiry 28 December, 2021.
Ethicon, Approved EMEA/UK Antibacterial Sutures VR video: 137522-200420. Expiry 28 June, 2021
Ethicon, Approved EMEA EXPECT MORE PLUS A UK CASE STUDY UK Story: 161984-201207. Expiry 6 July, 2023
Ethicon, Approved EMEA EXPECT MORE CZECH STUDY: 172550-210331. Expiry 7 July, 2023
Ethicon, Approved EMEA/UK Care4Today Recovery video: 181683-210630. Expiry 27 July, 2023
 

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