MultiLoc® Humeral Nailing System 

With the MultiLoc® Humeral Nailing System, DePuy Synthes opens up opportunities for the treatment of humeral fractures. The modular implant system, consists of a short and long nail with multiple locking options, in order to address simple and complex fractures. The straight nail design screw concept enables solutions for the individual patient.2

MultiLoc Humeral Nailing System

Features & Benefits

  • MultiLoc Humeral Nail
    Screw-in-Screw for Improved Fixation

    Screw-in-screw technology permits the treatment of proximal humeral fractures. 3.5 mm locking screws inserted through the heads of MultiLoc screws target the posteromedial region with strong bone mineral density (BMD), reducing instances of varus collapse and providing improved fixation in osteoporotic bone.1,2

  • MultiLoc Humeral Nail

    Ascending Screw Provides Medial Support

    Medial support enhances the stability of the osteosynthesis and allows for a more secure fixation of proximal humeral fractures, especially medially comminuted (varus-type) fractures.1,3,4

  • MultiLoc Humeral Nail

    Bicortical Compression for Stability

    Bicortical compression has a feature of the MultiLoc Humeral Nail (long), which provides rotational stability in transverse and short oblique fractures to support bone union. A locking screw is inserted bicortically below the axillary nerve. The mechanism holds compression intraoperatively, prior to insertion of additional screws in the proximal fragment.5,6 

  • MultiLoc Humeral Nail

    Multiplanar Distal Locking in Safe Zone

    Multiplanar distal locking reduces implant toggling in proximal humeral nailing. The MultiLoc Humeral Nail (long) includes distal locking planes respecting neurovascular structures.6-9


1. Dilisio MF, Nowinski RJ, Hatzidakis AM, Fehringer EV. Intramedullary nailing of the proximal humerus: evolution, technique, and results. Journal of Shoulder and Elbow Surgery. 2016;25(5) page 2.
2. Summary of Validation (0000236628 pages 1, 5-6) states that the 3.5 mm locking screw was implanted through the centering sleeve which provided improved fixation to the osteoporotic bone. The angular stable locking option in the nail enhances the biomechanical stability in osteoporotic bone.
3. Hao, T. D., & Huat, A. W. T. (2017). Surgical technique and early outcomes of intramedullary nailing of displaced proximal humeral fractures in an Asian population using a contemporary straight nail design. Journal of Orthopaedic Surgery. Page 6.
4. Rothstock, S., Plecko, M., Kloub, M., Schiuma, D., Windolf, M. and Gueorguiev, B. (2012). Biomechanical evaluation of two intramedullary nailing techniques with different locking options in a three-part fracture proximal humerus model. Clinical Biomechanics, 27(7), page 690.
5. Summary of Validation (0000236628 page 2) states that there is a bicortical compression feature designed to increase stability in transverse and short oblique fractures.
6. AO Principles: Section 6.2.2 page 619 Buckley RE, Moran CG, Apivatthakakul T. AO Principles of Fracture Management. 3rd ed. Stuttgart, Germany, New York: Thieme. 2017.
7. Stedtfeld HW, Mittlmeier T. “Fixation of Proximal Humeral Fractures with an Intramedullary Nail: Tips and Tricks.” Eur J Trauma Emerg Surg 33(2007): page 373.
8. Helfen et al. BMC Musculoskeletal Disorders (2016) 17:448. Page 6.
9. Summary of Validation (0000236628 page 2) states that the MultiLoc distal locking is designed to reduce implant toggeling. Improved distal locking is also designed to be in the safe zone between the median and radial nerve in the long nail.

Indication Statement

For product details such as indications, contraindications, warnings and precautions please consult the IFU and Surgical Technique.