Peer-Reviewed Evidence in Thoracic Surgery

ECHELON FLEX Powered Staplers vs. Medtronic Non-Powered Staplers Has Been Associated With:

Echelon Flex vs Medtronic non-powered
Echelon Flex vs Medtronic non-powered
Echelon Flex vs Medtronic non-powered

Your Choice of Stapler Matters

Surgical complications are costly and most importantly can be devastating for patients. In VATS lobectomy, air leaks and bleeding are among the most common complications, leading to increased morbidity, longer hospital stay and increased costs.

Ethicon is committed to evidence and advancing surgical care to improve patient care and outcomes. We recently completed peer-reviewed studies, which allow us to share compelling evidence that ECHELON FLEX™ Powered Staplers have been associated with improved clinical and economic outcomes compared to Medtronic non-powered staplers.¹

Your Choice of Stapler Matters

Improved Clincial & Economic Outcomes

Economic evidence from a peer-reviewed study demonstrated that improved hemostasis outcomes were associated with the use of ECHELON FLEX™ Powered Vascular Stapler plus another ECHELON FLEX™ Powered Stapler—without increasing costs in VATS lobectomy.5 Study published in Advances in Therapy.

Improved Clincial and Economic Outcomes

The Physiologic Lung Model

First and only benchtop model to simulate mechanical and physiologic breathing (positive and negative pressure), developed in partnership with clinical experts at Massachusetts General Hospital.

Model has the ability to collect and measure air leak source, incidence, and volume. 

The Physiologic Lung Model

2x Fewer Staple-Line Air Leaks8

A published study from the Physiologic Lung Model demonstrated that under physiologic breathing conditions, the ECHELON FLEX™ GST System resulted in fewer staple line air leaks compared to Endo GIA™ with Tri-Staple™ Technology.

2x Fewer Staple-Line Air Leaks
Evidence Through Innovation

Watch this video to learn more about the Physiologic Lung Model, a unique model designed to better understand air leaks under physiologic breathing conditions.

References

1. Ethicon retrospective analysis of economic and clinical outcomes comparing the use of Echelon Powered vs. Medtronic non-powered endoscopic surgical staplers to treat patients undergoing video-assisted thoracoscopic surgery lobectomy.Review of 3,006 cases between 2012 and 2015 from the Premier Perspective® Hospital Database. Data assessed included length of stay, total hospital cost, supply cost, room & board cost, incidence of transfusion, and incidence of hemostasis-related complications; all p ≤ 0.05.

2. Ethicon retrospective analysis of clinical outcomes between Echelon Powered vs. Medtronic non-powered endoscopic surgical staplers among patients undergoing video-assisted thoracoscopic surgery lobectomy. Review of 1,501 cases between 2012 and 2015 from the Premier Perspective® Hospital Database (4.8% vs. 14.2%;p=0.0098).

3. Ethicon retrospective analysis of economic and clinical outcomes between Echelon Powered vs. Medtronic non-powered endoscopic surgical staplers among patients undergoing video-assisted thoracoscopic surgery lobectomy. Review of 3,006 cases between 2012 and 2015 from the Premier Perspective® Hospital Database. Length of stay:4.9 vs 5.7 days; p=0.0374, Total hospital cost: $23,785 vs. $26,180; p=0.0078, Supply cost: $5,021 vs. $5,989; p=0.0161, Room & board cost: $6,792 vs. $7,984; p=0.0385, Transfusion: 4.7% vs. 9.3%; p=0.018, Hemostasis-related complications: 8.2% vs. 13.9%; p=0.0218.

4. Ethicon retrospective analysis of outcomes between Echelon Powered vs. Medtronic non-powered endoscopic surgical staplers among patients undergoing video-assisted thoracoscopic surgery lobectomy. Review of 1,051 cases between 2012 and 2015 from the Premier Perspective® Hospital Database. Hemostasis-related complications: 4.8% vs. 14.2%; p=0.010. Transfusion: 3.0% vs. 9.4%; p=0.023. Total hospital costs: $23,219 vs. $25,207; p=0.242.

5. Ethicon retrospective analysis of clinical outcomes between Echelon Powered vs. Medtronic non-powered endoscopic surgical staplers among patients undergoing video-assisted thoracoscopic surgery lobectomy. Review of 1,051 cases between 2012 and 2015 from the Premier Perspective® Hospital Database (4.8% vs. 14.2%;p=0.0098).

6. Compared to the Endo GIA™ Curved Tip Reload with Tri-Staple™ Technology. PVE35A, EGIA30CTAVM, and PSE45A articulation data from IFUs of each device

7. Challenging tissue—thick, fragile, and varying thickness and density

8. Staple line air leaks in porcine lungs using a physiologically-based ex-vivo lung chamber model.   ECHELON FLEX™ GST System vs Endo GIA™ with Tri-Staple™ Technology.  20% vs 44%, GST 45 Blue (n=25) & Green (n=30) reloads vs Tri-Staple™ 45 Purple (n=25) & Black (n=30).  Based on similar design features between ECHELON GST45 & GST60, no significant difference in performance is expected.


For complete indications, contraindications, warnings, precautions, and adverse reactions, please reference full package insert.