For 1 Million Knees, A Step in the Right Direction

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Osteoarthritis (OA) is the most prevalent joint disease, affecting 27 million US adults, with knee OA accounting for more than 80% of the total disease burden.1,2 For 125 years, DePuy Synthes, a Johnson & Johnson Medical Devices Company, has been committed to improving patient outcomes and evolving to meet the next frontier of modern surgery. Recently, DePuy Synthes announced that more than 1 million patients globally have been implanted with the ATTUNE® Knee System.

The ATTUNE Knee System by DePuy Synthes has improved functional outcomes for OA patients and helps patients get back to doing what they love.3 “This implant was designed to consider every potential design iteration,” said Dr. Douglas Dennis, Orthopaedic Surgeon. “The staying power of the ATTUNE Knee’s diverse portfolio goes hand-in-hand with the rapidly evolving knee OA landscape.”

By combining the latest in design, kinematics, engineering and materials, DePuy Synthes continues to expand the ATTUNE Knee Platform to provide state-of-the-art knee solutions. Products such as the ATTUNE Cementless Knee System and the ATTUNE Revision Knee System are designed to meet the full spectrum of patient and surgeon needs. “In my experience with ATTUNE, patients are able to get back to work and activities quicker than they would in the past. Happier patients lead to happier surgeons,” said Dr. William P. Barrett, ATTUNE Knee Surgeon Innovator.

While knee replacement surgery is a common and successful procedure, it’s important for both patients and their surgeons to have confidence in the knee system they choose.4 As patient-centered care continues to drive medical innovation, patient-reported outcomes measures (PROMs) are important benchmarks to understand patients’ perceptions of their health and recovery, as well as the quality and satisfaction of care they receive.

Interim results of two worldwide, multi-center prospective studies showed that the ATTUNE Knee System had significantly improved outcomes, compared to other leading knee systems, across a broad range of PROMs, including Quality of Life, Activities of Daily Living, Pain, Sports & Recreation at a minimum one-year follow up.3 “The ATTUNE Knee System is designed to work in harmony with my patients’ native knee muscles and ligaments to increase stability and reduce pain,” said Dr. Dennis. “For my Total Knee Replacement (TKR) patients, to be able to hear the positive impact it has had on their quality of life continues to be one of the most rewarding aspects of my career.”


1 Moskowitz, R.W., (2009). The burden of osteoarthritis: clinical and quality-of-life issues. The American Journal of Managed Care, 15(8 Suppl): S223-9, PMID:19817508, https://europepmc.org/abstract/med/19817508.
Wallace, I.J., et al. (2017). Knee osteoarthritis has doubled in prevalence since the mid-20th century. PNAS.Vol. 114: 9332-9336.
Hamilton, W.G., et al. Early Patient Reported Outcomes with New Primary vs. Contemporary Total Knee Arthroplasty: A Comparison of Two, Worldwide, Multi-Center Prospective Studies. E-poster-ISTA 2016.
Foran, J.R.H., (2020). Total Knee Replacement. The American Academy of Orthopaedic Surgeons. Accessed August 17, 2020. https://orthoinfo.aaos.org/en/treatment/total-knee-replacement.

Beyond implant technology, DePuy Synthes is investing in innovations across the care continuum to further improve patient satisfaction and outcomes, and working with hospitals and health systems to increase the value of TKR for both patients and surgeons. At DePuy Synthes and Johnson & Johnson Medical Devices Companies, we are tackling pressing healthcare challenges, and take bold steps that lead to new standards of care while improving people's healthcare experiences. For more information on ATTUNE Knee System data, please visit ATTUNEevidence.com. Find resources for your patients at ATTUNEKnee.com.

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