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Surgical Stapling
Backed by a Body of Evidence
ECHELON products are designed for exceptional tissue management and control. It's the only portfolio that goes "beyond the benchtop," using real-world evidence in colorectal, bariatric and thoracic surgery to support innovative performance and design for a better way to staple.
Body of Evidence: Colorectal
The ECHELON CIRCULAR™ Powered Stapler demonstrated anastomotic leak rates of 1.8% and 1.7% in two clinical studies.†§ It has an innovative combination of Gripping Surface Technology and 3D Stapling Technology and it reduced leaks at the staple line without compromising perfusion.*
The ECHELON CIRCULAR™ Powered Stapler demonstrated the following clinical results in colorectal surgery.
1.8%
anastomotic leak rate in a multi-site, multicountry clinical study (3/168)†
1.7%
anastomotic leak rate in a single institution clinical study (1/60)§
85%
reduction in anastomotic leak rate compared to manual circular staplers (1.7% v. 11.8%, p=0.02)§
Body of Evidence: Bariatric
The ECHELON FLEX™ Powered Plus Stapler with GST Reloads is backed by retrospective studies demonstrating associated reductions in complications and cost.3 It's designed with two-stage compression to reduce the forces exerted on the tissue during firing—even in challenging tissue¶
ECHELON FLEX™ Powered Staplers with GST Reloads are the only surgical staplers backed by large-scale, real-world, peer-reviewed evidence associated with improved clinical and economic outcomes in bariatric surgery.
Up to 73%
reduction in hemostasis-related complications vs Medtronic Signia™ with Tri-StapleTM Reload (0.67% vs 2.51%, p=0.003)2
7%
lower median total hospital cost vs Medtronic Signia™ with Tri-StapleTM Reload ($9,771 vs $10,487, p<0.001)2
Body of Evidence: Thoracic
The ECHELON FLEX™ Powered Vascular Stapler plus ECHELON FLEX™ Powered Stapler with GST has been shown through retrospective studies to be associated with the reduction of complications without an increase in price.3 GST offers two-stage compression and stability while PVS offers improved access and precision via a narrow anvil, increased articulation, and smaller shaft diameter for vascular firings.
The ECHELON FLEX™ Powered Vascular Stapler plus the ECHELON FLEX™ Powered Stapler with GST are supported through real-world evidence and were associated with improved hemostasis outcomes without increasing cost in thoracic surgery.
66%
reduction in bleeding-related complications (4.8% vs 14.2%, p=0.01)4
14%
reduction in length of stay (4.99 vs 5.82, p=0.047)5
No
increase in hospital costs compared to using a single Medtronic stapler6
All Surgical Stapling Products
References
* Benchtop testing in porcine tissue ≤30mmHg (26mmHg average pressure experienced during intra-operative leak test), comparing Ethicon CDH29P to Medtronic EEA2835 (p<0.001) and preclinical perfusion model, in which perfusion was not significantly different between devices.
† A Prospective, Multi Center Evaluation of the ECHELON CIRCULAR Powered Stapler in Left–Sided Colorectal Anastomoses, N=168.
§ Impact of the Novel Powered Circular Stapler on Risk of Anastomotic Leakage in Colorectal Anastomosis. A Propensity Score-Matched Study. [ECHELON CIRCULAR 1.7% (1/60) vs. manual circular 11.8% (14/119), p=0.022]
¶ Challenging tissue - thick, fragile, and varying thickness and density
1. Based on literature search performed May 2019. Large-scale is defined as sample size greater than 3500 cases.
2. Rawlins L, Johnson BH, Johnston SS, et al. Comparative Effectiveness Assessment of Two Powered Surgical Stapling Platforms in Laparoscopic Sleeve Gastrectomy: A Retrospective Matched Study. Medical Devices: Evidence and Research. 2020:13 195–204. doi: https://doi.org/10.2147/MDER.S256237. Analysis of clinical and economic outcomes from 982 laparoscopic sleeve gastrectomy cases between March 1, 2017 and December 31, 2018 from Premier Healthcare Database (0.61% versus 2.24%, p=0.0012; $9,771 vs. $10,487, p<0.001)
3. Miller DL, Roy S, Kassis ES, Yadalam S, Ramisetti S, Johnston SS. Impact of powered and tissue-specific endoscopic stapling technology on clinical and economic outcomes of video-assisted thoracic surgery lobectomy procedures: a retrospective, observational study. Adv Ther. 2018;35(5):707-723.
4. Miller DL, et al. Impact of powered and tissue-specific endoscopic stapling technology on clinical and economic outcomes of video-assisted thoracic surgery lobectomy procedures: a retrospective, observational study. Review of 1,051 cases between 2015 and 2016 from the Premier Healthcare Database (4.8% vs 14.2%, p=0.010).
5. Miller DL, Roy S, Kassis ES, et al. Impact of Powered and Tissue-Specific Endoscopic Stapling Technology on Clinical and Economic Outcomes of Video-Assisted Thoracic Surgery Lobectomy Procedures: A Retrospective, Observational Study. Adv Ther. 2018 Apr 16. doi: 10.1007/s12325-018-0679-z. Review of 1,051 cases between 2015 and 2016 from the Premier Healthcare Database. Length of stay: 4.99 vs 5.82, p=0.047.
6. Miller DL, Roy S, Kassis ES, et al. Impact of Powered and Tissue-Specific Endoscopic Stapling Technology on Clinical and Economic Outcomes of Video-Assisted Thoracic Surgery Lobectomy Procedures: A Retrospective, Observational Study. Adv Ther. 2018 Apr 16. doi: 10.1007/s12325-018-0679-z. Review of 3,006 cases between 2012 and 2016 from the Premier Healthcare Database ($23,785 vs $26,180, p=0.0078).
