DBX® Demineralized Bone Matrix (CMF)

DBX® Demineralized Bone Matrix (DBM) is an allograft bone void filler processed by the Musculoskeletal Transplant Foundation (MTF).

DBX Demineralized Bone Matrix Hero

Features & Benefits

DBX® DBM is an osteoconductive bone void filler which has been shown to have osteoinductive potential* in a validated athymic mouse model. Each finished lot of tissue is tested for osteoinductive potential prior to release for clinical use. DBX DBM is ideal for a variety of applications within the cleared indications.

DBX DBM

  • Available as Paste, Putty, Mix, and Injectable Putty
  • Demonstrated bone formation – high bone content, osteoinductive potential, histologic verification1
  • Inert biocompatible carrier2, pH-balanced3, nonhemolytic2
  • Resists movement under irrigation, maintains physical integrity4

Supporting Documentation

Resources

DBX Demineralized Bone Matrix Inventory Control Chart

DBX Demineralized Bone Matrix Inventory Control Form

DBX Demineralized Bone Matrix, CONFORM Cube & CONFORM Sheet Inventory Control Form

Osteoinductivity of MTF DBX Putty White Paper

References

*It is unknown how the osteoinductive potential, measured in the athymic mouse model or the alkaline phosphatase assay, will correlate with clinical performance in human subjects.1
1. Dunn, Michael G. Osteoinductivity of MTF DBX® Putty in the Athymic Mouse Model. Musculskeletal Transplant Foundation. Oct. 2011.
2. MTF Report# 19-001R MM
3. MTF Report# FR-39 4. Gertzman, A. and M. Sunwoo. “A pilot study evaluating sodium hyaluronate as a carrier for freeze-dried demineralized bone powder”. Cell and Tissue Banking, 2001(2): p. 87-94.

DBX is a registered trademark of MTF.

Indication Statement

DBX® Demineralized Bone Matrix Paste & Mix

DBX Paste and DBX Mix are intended for use as a Demineralized Bone Matrix for voids or gaps that are not intrinsic to the stability of the bony structure. DBX Paste and DBX Mix are indicated for treatment of surgically created osseous defects or osseous defects created from traumatic injury.

DBX Inject™ Demineralized Bone Matrix Putty

DBX Inject is intended for use as a Demineralized Bone Matrix for voids or gaps that are not intrinsic to the stability of the bony structure. DBX Inject is indicated for treatment of surgically created osseous defects or osseous defects created from traumatic injury.

DBX® Demineralized Bone Matrix Putty

DBX Putty is intended for use as a Demineralized Bone Matrix for voids or gaps that are not intrinsic to the stability of the bony structure. DBX Putty is indicated for treatment of surgically created osseous defects or osseous defects created from traumatic injury.
*Please refer to IFU for complete list of indications, contraindications, warnings, and precautions.

114883-190522 DSUS