DERMABOND® PRINEO® Skin Closure System

DERMABOND® PRINEO® combines the proven strength, flexibility, and microbial barrier of DERMABOND ADVANCED® with the security of a self-adhering mesh to facilitate skin closure and an optimal healing environment.1-6

DERMABOND® PRINEO® Skin Closure System

Features & Benefits

Readmission Rates DERMABOND PRINEO Skin Closure System v. Staples

Shorter length of stay and fewer return visits

DERMABOND® PRINEO® has no dressings to change or staples to remove. Patients with DERMABOND® PRINEO® had a shorter length of stay and lower readmissions than patients with skin staples in total knee arthroplasty.7

DERMABOND PRINEO Skin Closure System - caring for your incision at home

Simplified at-home care

With its transparent barrier that allows for observation of the incision, DERMABOND® PRINEO® may be especially suitable for surgeons who have adopted telemedicine protocols in their post‐op patient care. Patients may be able to shower immediately after their procedure, if directed by the healthcare professional.4

Microbial barrier

Microbial barrier

The microbial barrier protection of DERMABOND® PRINEO® is proven 99% effective through 72 hours in vitro.8 Furthermore, DERMABOND® PRINEO® is demonstrated in vitro to kill 99.9% of bacteria (MRSA, MRSE, and E Coli) on direct contact.9†

Comparative Holding Strength DERMABOND PRINEO Skin Closure System v. Staples v. Suture

Stronger, more secure closure

DERMABOND® PRINEO® was shown to provide statistically significant greater skin holding strength than skin staples or subcuticular suture.10‡

Videos

Resources

A Case for Wound Coverage: Why the need for air exposure is just a myth
A Case for Wound Coverage: Why the need for air exposure is just a myth
03:42
Total Knee Arthroplasty with Dr. Nunley
Total Knee Arthroplasty with Dr. Nunley
01:17
Total Abdominal Hysterectomy with Dr. Thad Deheny
Total Abdominal Hysterectomy with Dr. Thad Deheny
02:52
Spine Deformity Surgery with Dr. Suken Shah
Spine Deformity Surgery with Dr. Suken Shah
02:46
Anterior Spine Surgery with Dr. Christopher Cain
Anterior Spine Surgery with Dr. Christopher Cain
04:33
Total Hip Arthroplasty with Dr. Nunley
Total Hip Arthroplasty with Dr. Nunley
06:49
Optimal Wound Healing with DPSCS (Dr. Ovington)
Optimal Wound Healing with DPSCS (Dr. Ovington)
05:23
Patient Journey: Watch Diane's experience with DERMABOND® PRINEO®
Patient Journey: Watch Diane's experience with DERMABOND® PRINEO®
03:32

Supporting Documentation

Product Support

DERMABOND® PRINEO® Skin Closure System Brochure

DERMABOND PRINEO System 22 Information Sheet

DERMABOND® PRINEO® Complies with Guidelines for Resuming Elective Surgery During the Pandemic

DERMABOND® PRINEO® in Labor and Delivery

DERMABOND PRINEO System Patient Care Pad

Clinical Evidence

DERMABOND® PRINEO® Skin Closure System Evidence Brief

DERMABOND PRINEO Patient Surgeon Satisfaction Study

DERMABOND® PRINEO® C-section Study

DERMABOND® PRINEO® FAQ

DERMABOND PRINEO Dermatitis Study Stat

DERMABOND PRINEO Total Knee Arthroplasty Study

C-Section Value Brief

Dr. Snyder/TriHealth Case Study

Proliance Case Study

References

*In a retrospective, observational study using the Premier Healthcare Database in total knee arthroplasty (N=1,942), 2012-2015; LOS 2.8 days vs 3.2, P=0.002; discharge to SNF 26% vs 39%, P=0.011; 30-day readmissions 1.8 vs 4.4%, P=0.006).

†Clinical significance unknown.

‡In an ex vivo study, more load in N was required to create a 3 ±1 mm gap between skin edges approximated with DERMABOND PRINEO System, than with subcuticular 4-0 MONOCRYL® Suture or PROXIMATE® Ethicon Endo-Surgery skin staples (P=0.00).

1. Keplinger S. Protocol investigation of the comparison of PRINEO with conventional wound closure techniques. 07PD048. May 2007. Ethicon, Inc.

2. Richter D. Multi-centre study to show equivalence of DERMABOND PROTAPE to INTRADERMAL SUTURES for skin closure of full thickness surgical incisions associated with breast procedures. 07CS003. Final Report 09 July 2010. Ethicon, Inc.

3. Richter D. Multi-centre study to show equivalence of DERMABOND PROTAPE to INTRADERMAL SUTURES for skin closure of full thickness surgical incisions. 06CS005. Final Report 10 June 2010. Ethicon, Inc.

4. DERMABOND® PRINEO® Skin Closure System (22 cm), Instructions for Use. Ethicon, Inc.

5. Shapiro AJ, Dinsmore RC, North JH. Tensile strength of wound closure with cyanoacrylate glue. Am Surg. 2001;67(11):1113-1115. 

6. Kannon GA, Garrett AB. Moist wound healing with occlusive dressings. A clinical review. Dermatol Surg. 1995;21(7):583-590.

7. Sutton N, Schmitz ND, Johnston SS. Economic and clinical comparison of 2-octyl cyanoacrylate/polymer mesh tape with skin staples in total knee replacement. J Wound Care. 2018;27(Sup4):S12-S22.

8. Su W. Study Report for in vitro evaluation of microbial barrier properties of DERMABOND ProTape. Report Number 06TR071. December 4, 2006. Ethicon, Inc.

9. Bhende S. In-vitro study to evaluate the ability of DERMABOND™ PRINEO™ Skin Closure System to kill bacteria on contact. June 22, 2012. Ethicon, Inc.

10. Kumar A. Study to Compare the tissue holding strength of PRINEO™ skin closure system with conventional wound closure techniques. AST-2012-0290. 2012. Ethicon, Inc.