MONOCRYL® Plus Antibacterial (poliglecaprone 25) Suture

MONOCRYL Plus Sutures are ideal for subcuticular skin closure1 and shown in vitro to inhibit bacterial colonization of the suture.2 They provide 1-2 weeks of tissue support.1

MONOCRYL® Plus Antibacterial (poliglecaprone 25) Suture

Features & Benefits

MONOCRYL Plus Antibacterial Sutures - reduction in surgical site infection risk

Shown to reduce SSI risk, supported by Level 1A evidence3,4

Meta-analysis—considered Level 1A evidence4—demonstrated a 28% reduction in surgical site infection (SSI) risk with the use of triclosan-coated sutures.3*† In the same study, meta-regression analysis demonstrated that the effect of triclosan-coated sutures in reducing the risk of SSI did not vary by CDC wound classification or suture type.3*†‡ 

MONOCRYL Plus Antibacterial Sutures -  are a low cost part of hospital acquired infection prevention

A cost-effective part of an SSI-prevention bundle

A single SSI can cost up to $39,000.6|| But, at up to $5 more per surgery than traditional sutures, Plus Sutures are an affordable part of the SSI-prevention care bundle recommended by the World Health Organization (WHO).  

Triclosan coated sutures are included in SSI prevention bundles recommended by WHO CDC ACS SIS NICE

Recommended by 6 independent authorities

Triclosan-coated sutures are included in SSI-prevention bundles recommended by the CDC, ACS/SIS, WHO, NICE, and RKI.6-10 

Ethicon also offers barbed suture - STRATAFIX Knotless Tissue Control Devices

Benefit from Plus Antibacterial Technology in barbed sutures, too

STRATAFIX™ Knotless Tissue Control Devices, made from the same polymers as traditional Ethicon sutures, are the only commercially available barbed sutures with triclosan, which inhibits methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus epidermidis (MRSE), and other bacteria linked to SSIs.12 #**††

Resources

Resources

Understanding the Plus Antibacterial Technology
Understanding the Plus Antibacterial Technology
04:45
The Fight Against SSI
The Fight Against SSI
03:16

Supporting Documentation

Product Support

Plus Antibacterial Sutures Portfolio Overview

Plus Suture Conversion Guide

Wound Closure Product Catalog

Clinical Evidence
 

Plus Sutures Evidence Summary

Plus Sutures de Jonge Meta-Analysis Overview

Product Specifications

Product Code

Product Code

Description

 
D10041 D10041 2-0 MONOCRYL PLUS UNDYED 1X27" PS-1 

Product Code

Product Code

Description

 
D10062 D10062 4-0 MONOCRYL PLUS UNDYED 1X18" P-2 

Product Code

Product Code

Description

 
D10100 D10100 3-0 MONOCRYL PLUS VIOLET 1X27" RB-1 

Product Code

Product Code

Description

 
D10101 D10101 3-0 MONOCRYL PLUS UNDYED 1X27" RB-1 

Product Code

Product Code

Description

 
D9923 D9923 2-0 MONOCRYL PLUS UNDYED 1X27" RB-1 

Product Code

Product Code

Description

 
D9924 D9924 2-0 MONOCRYL PLUS VIOLET 1X27" RB-1 

Product Code

Product Code

Description

 
D9925 D9925 1 MONOCRYL PLUS UNDYED 1X27" MO-5 

Product Code

Product Code

Description

 
D9936 D9936 2-0 MONOCRYL PLUS VIOLET 1X36" SH-1 DOUBLE ARMED 

Product Code

Product Code

Description

 
D9937 D9937 2-0 MONOCRYL PLUS UNDYED 1X36" SH-1 DOUBLE ARMED 

Product Code

Product Code

Description

 
D9954 D9954 4-0 MONOCRYL PLUS UNDYED 1X27" P-3 DOUBLE ARMED 

Product Code

Product Code

Description

 
MCP213H MCP213H 5-0 MONOCRYL PLUS UNDYED 1X27" RB-1 

Product Code

Product Code

Description

 
MCP214H MCP214H 4-0 MONOCRYL PLUS UNDYED 1X27" RB-1 

Product Code

Product Code

Description

 
MCP266H MCP266H 2-0 MONOCRYL PLUS UNDYED 1X27" CP-1 

Product Code

Product Code

Description

 
MCP304H MCP304H 4-0 MONOCRYL PLUS VIOLET 1X27" RB-1 

Product Code

Product Code

Description

 
MCP315H MCP315H 4-0 MONOCRYL PLUS VIOLET 1X27" SH 

Product Code

Product Code

Description

 
MCP316H MCP316H 3-0 MONOCRYL PLUS VIOLET 1X27" SH 

Product Code

Product Code

Description

 
MCP317H MCP317H 2-0 MONOCRYL PLUS VIOLET 1X27" SH 

Product Code

Product Code

Description

 
MCP333H MCP333H 2-0 MONOCRYL PLUS VIOLET 1X27" CT-2 

Product Code

Product Code

Description

 
MCP339H MCP339H 2-0 MONOCRYL PLUS VIOLET 1X27" CT-1 

Product Code

Product Code

Description

 
MCP340H MCP340H 0 MONOCRYL PLUS VIOLET 1X27" CT-1 

References

*21 RCTs, 6462 patients, 95% CI: (14, 40%), P<0.001.

†All triclosan-coated sutures in these RCTs were Ethicon Plus Antibacterial Sutures (MONOCRYL® Plus Antibacterial [poliglecaprone 25] Suture, Coated VICRYL® Plus Antibacterial [polyglactin 910] Suture, and PDS® Plus Antibacterial [polydioxanone] Suture).

‡Clean wounds 10 RCTs, 2842 patients, 95% CI: (11-43%), P=0.003; non-clean wounds 14 RCTs, 3620 patients, 95% CI: (7-42%). 

§On average, compared to traditional sutures.

||As shown in coronary artery bypass surgery. 

¶Guidelines on reducing the risk of surgical site infections are general to triclosan-coated sutures and are not specific to any one brand.

#PDS Plus and MONOCRYL Plus sutures only.

**Staphylococcus aureus, Staphylococcus epidermidis, methicillin-resistant Staphylococcus aureus (MRSA), methicillin-resistant Staphylococcus epidermidis (MRSE), Escherichia coli, and Klebsiella pneumoniae. 

††Refers only to STRATAFIX™ Symmetric PDS™ Plus, STRATAFIX™ Spiral PDS™ Plus, and STRATAFIX™ Spiral Monocryl™ Plus. 

1. MONOCRYL® Plus Antibacterial (poliglecaprone 25) Suture Instructions for Use. Ethicon, Inc. 

2. Ming X, Rothenburger S, Yang D. In vitro antibacterial efficacy of Monocryl Plus Antibacterial Suture (poligelcaprone 25 with triclosan). Surg Infect (Larchmt). 2007;8(2):201-208.

3. de Jonge SW, Atema JJ, Solomkin JS, Boermeester MA. Meta-analysis and trial sequential analysis of triclosan-coated sutures for the prevention of surgical-site infection. Br J Surg. 2017;104(2):e118-e133.

4. Oxford Centre for Evidence-based Medicine. Levels of Evidence. March, 2009. https://www.cebm.net/2009/06/oxford-centre-evidence-based-medicine-levels-evidence-march-2009/. Accessed September 8, 2020. 

5. Plus Suture Cost Analysis. 2019. Ethicon, Inc.

6. de Lissovoy G, Pan F, Paktar A, et al. Surgical site infection incidence and burden assessment using multi-national real-world data. Presented at EU ISPOR Meeting; November 5-8, 2011; Madrid, Spain.

7. World Health Organization Global Guidelines for the Prevention of Surgical Site Infection, 2018. https://apps.who.int/iris/bitstream/handle/10665/277399/9789241550475-eng.pdf. Accessed May 9, 2020.

8. Berríos-Torres SI, Umscheid CA, Bratzler DW, et al. Centers for Disease Control and Prevention guideline for the prevention of surgical site infection, 2017. JAMA Surg. 2017;152(8):784-791. doi:10.1001/jamasurg.2017.0904.

9.  Ban KA, Minei JP, Laronga C, et al. American College of Surgeons and Surgical Infection Society: surgical site infection guidelines, 2016 update. J Am Coll Surg. 2016;224(1):59-74. 

10.  National Institute for Health and Care Excellence (NICE) guideline. Surgical site infections: prevention and treatment. NICE website. https://www.nice.org.uk/guidance/ng125/chapter/Recommendations#closure-methods. Accessed July 2, 2020. 

11. Prevention of postoperative wound infections. Recommendation of the Committee for Hospital Hygiene and Infection Prevention (KRINKO) at the Robert Koch Institute. Bundesgesundheitsbl. 2018;61(4):448-473.

12. Bhende S, Burkley D, Nawrocki J. In vivo and in vitro anti-bacterial efficacy of absorbable barbed polydioxanone monofilament tissue control device with triclosan. Surg Infect (Larchmt). 2018;19(4):430-437.