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Features & Benefits

Shown to reduce SSI risk, supported by Level 1A evidence3,4
Meta-analysis—considered Level 1A evidence4—demonstrated a 28% reduction in surgical site infection (SSI) risk with the use of triclosan-coated sutures.3*† In the same study, meta-regression analysis demonstrated that the effect of triclosan-coated sutures in reducing the risk of SSI did not vary by CDC wound classification or suture type.3*†‡

A cost-effective part of an SSI-prevention bundle
A single SSI can cost up to $39,000.6|| But, at up to $5 more per surgery than traditional sutures,5§ Plus Sutures are an affordable part of the SSI-prevention care bundle recommended by the World Health Organization (WHO).7¶

Recommended by 6 independent authorities¶
Triclosan-coated sutures are included in SSI-prevention bundles recommended by the CDC, ACS/SIS, WHO, NICE, and RKI.6-10

Benefit from Plus Antibacterial Technology in barbed sutures, too
STRATAFIX™ Knotless Tissue Control Devices, made from the same polymers as traditional Ethicon sutures, are the only commercially available barbed sutures with triclosan, which inhibits methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus epidermidis (MRSE), and other bacteria linked to SSIs.12 #**††
Resources
Resources
Resources


Supporting Documentation
Product Support
Plus Antibacterial Sutures Portfolio Overview
Plus Suture Conversion Guide
Wound Closure Product Catalog
Clinical Evidence
Plus Sutures Evidence Summary
Plus Sutures de Jonge Meta-Analysis Overview
Product Specifications
Product Code |
Product Code |
Description |
---|---|---|
D10041 | D10041 | 2-0 MONOCRYL PLUS UNDYED 1X27" PS-1 |
Product Code |
Product Code |
Description |
---|---|---|
D10062 | D10062 | 4-0 MONOCRYL PLUS UNDYED 1X18" P-2 |
Product Code |
Product Code |
Description |
---|---|---|
D10100 | D10100 | 3-0 MONOCRYL PLUS VIOLET 1X27" RB-1 |
Product Code |
Product Code |
Description |
---|---|---|
D10101 | D10101 | 3-0 MONOCRYL PLUS UNDYED 1X27" RB-1 |
Product Code |
Product Code |
Description |
---|---|---|
D9923 | D9923 | 2-0 MONOCRYL PLUS UNDYED 1X27" RB-1 |
Product Code |
Product Code |
Description |
---|---|---|
D9924 | D9924 | 2-0 MONOCRYL PLUS VIOLET 1X27" RB-1 |
Product Code |
Product Code |
Description |
---|---|---|
D9925 | D9925 | 1 MONOCRYL PLUS UNDYED 1X27" MO-5 |
Product Code |
Product Code |
Description |
---|---|---|
D9936 | D9936 | 2-0 MONOCRYL PLUS VIOLET 1X36" SH-1 DOUBLE ARMED |
Product Code |
Product Code |
Description |
---|---|---|
D9937 | D9937 | 2-0 MONOCRYL PLUS UNDYED 1X36" SH-1 DOUBLE ARMED |
Product Code |
Product Code |
Description |
---|---|---|
D9954 | D9954 | 4-0 MONOCRYL PLUS UNDYED 1X27" P-3 DOUBLE ARMED |
Product Code |
Product Code |
Description |
---|---|---|
MCP213H | MCP213H | 5-0 MONOCRYL PLUS UNDYED 1X27" RB-1 |
Product Code |
Product Code |
Description |
---|---|---|
MCP214H | MCP214H | 4-0 MONOCRYL PLUS UNDYED 1X27" RB-1 |
Product Code |
Product Code |
Description |
---|---|---|
MCP266H | MCP266H | 2-0 MONOCRYL PLUS UNDYED 1X27" CP-1 |
Product Code |
Product Code |
Description |
---|---|---|
MCP304H | MCP304H | 4-0 MONOCRYL PLUS VIOLET 1X27" RB-1 |
Product Code |
Product Code |
Description |
---|---|---|
MCP315H | MCP315H | 4-0 MONOCRYL PLUS VIOLET 1X27" SH |
Product Code |
Product Code |
Description |
---|---|---|
MCP316H | MCP316H | 3-0 MONOCRYL PLUS VIOLET 1X27" SH |
Product Code |
Product Code |
Description |
---|---|---|
MCP317H | MCP317H | 2-0 MONOCRYL PLUS VIOLET 1X27" SH |
Product Code |
Product Code |
Description |
---|---|---|
MCP333H | MCP333H | 2-0 MONOCRYL PLUS VIOLET 1X27" CT-2 |
Product Code |
Product Code |
Description |
---|---|---|
MCP339H | MCP339H | 2-0 MONOCRYL PLUS VIOLET 1X27" CT-1 |
Product Code |
Product Code |
Description |
---|---|---|
MCP340H | MCP340H | 0 MONOCRYL PLUS VIOLET 1X27" CT-1 |
References
*21 RCTs, 6462 patients, 95% CI: (14, 40%), P<0.001.
†All triclosan-coated sutures in these RCTs were Ethicon Plus Antibacterial Sutures (MONOCRYL® Plus Antibacterial [poliglecaprone 25] Suture, Coated VICRYL® Plus Antibacterial [polyglactin 910] Suture, and PDS® Plus Antibacterial [polydioxanone] Suture).
‡Clean wounds 10 RCTs, 2842 patients, 95% CI: (11-43%), P=0.003; non-clean wounds 14 RCTs, 3620 patients, 95% CI: (7-42%).
§On average, compared to traditional sutures.
||As shown in coronary artery bypass surgery.
¶Guidelines on reducing the risk of surgical site infections are general to triclosan-coated sutures and are not specific to any one brand.
#PDS Plus and MONOCRYL Plus sutures only.
**Staphylococcus aureus, Staphylococcus epidermidis, methicillin-resistant Staphylococcus aureus (MRSA), methicillin-resistant Staphylococcus epidermidis (MRSE), Escherichia coli, and Klebsiella pneumoniae.
††Refers only to STRATAFIX™ Symmetric PDS™ Plus, STRATAFIX™ Spiral PDS™ Plus, and STRATAFIX™ Spiral Monocryl™ Plus.
1. MONOCRYL® Plus Antibacterial (poliglecaprone 25) Suture Instructions for Use. Ethicon, Inc.
2. Ming X, Rothenburger S, Yang D. In vitro antibacterial efficacy of Monocryl Plus Antibacterial Suture (poligelcaprone 25 with triclosan). Surg Infect (Larchmt). 2007;8(2):201-208.
3. de Jonge SW, Atema JJ, Solomkin JS, Boermeester MA. Meta-analysis and trial sequential analysis of triclosan-coated sutures for the prevention of surgical-site infection. Br J Surg. 2017;104(2):e118-e133.
4. Oxford Centre for Evidence-based Medicine. Levels of Evidence. March, 2009. https://www.cebm.net/2009/06/oxford-centre-evidence-based-medicine-levels-evidence-march-2009/. Accessed September 8, 2020.
5. Plus Suture Cost Analysis. 2019. Ethicon, Inc.
6. de Lissovoy G, Pan F, Paktar A, et al. Surgical site infection incidence and burden assessment using multi-national real-world data. Presented at EU ISPOR Meeting; November 5-8, 2011; Madrid, Spain.
7. World Health Organization Global Guidelines for the Prevention of Surgical Site Infection, 2018. https://apps.who.int/iris/bitstream/handle/10665/277399/9789241550475-eng.pdf. Accessed May 9, 2020.
8. Berríos-Torres SI, Umscheid CA, Bratzler DW, et al. Centers for Disease Control and Prevention guideline for the prevention of surgical site infection, 2017. JAMA Surg. 2017;152(8):784-791. doi:10.1001/jamasurg.2017.0904.
9. Ban KA, Minei JP, Laronga C, et al. American College of Surgeons and Surgical Infection Society: surgical site infection guidelines, 2016 update. J Am Coll Surg. 2016;224(1):59-74.
10. National Institute for Health and Care Excellence (NICE) guideline. Surgical site infections: prevention and treatment. NICE website. https://www.nice.org.uk/guidance/ng125/chapter/Recommendations#closure-methods. Accessed July 2, 2020.
11. Prevention of postoperative wound infections. Recommendation of the Committee for Hospital Hygiene and Infection Prevention (KRINKO) at the Robert Koch Institute. Bundesgesundheitsbl. 2018;61(4):448-473.
12. Bhende S, Burkley D, Nawrocki J. In vivo and in vitro anti-bacterial efficacy of absorbable barbed polydioxanone monofilament tissue control device with triclosan. Surg Infect (Larchmt). 2018;19(4):430-437.
© Ethicon US, LLC. 2019. 085133-171129
For complete indications, contraindications, warnings, precautions, and adverse reactions, please reference full package insert.
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Last updated February 20, 2019. The third-party trademarks used herein are trademarks of their respective owners. Data and usage fees may apply. See your carrier for more information.