PDS® Plus Antibacterial (polydioxanone) Suture

With 4 to 6 weeks of tissue support, PDS Plus Sutures are particularly useful when you need a combination of an absorbable suture and extended wound support.1 Inhibition of bacterial colonization on the suture was shown in vitro and in vivo.2

PDS® Plus Antibacterial (polydioxanone) Suture

Resources

Supporting Documentation

Product Support

ETHICON Plus Antibacterial Sutures Brochure

Plus Antibacterial Suture Conversion Chart

Wound Closure Catalog

Clinical Evidence

Plus Sutures Evidence Summary

Plus Sutures de Jonge Meta-Analysis Overview

Product Specifications

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D10043 D10043 0 PDS PLUS VIOLET 1X27" UR-6 

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D10044 D10044 0 PDS PLUS VIOLET 1X27" MO-6 

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D10049 D10049 0 PDS PLUS VIOLET 1X36" CT-3 

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D10059 D10059 1 PDS PLUS VIOLET 1X60" TP-1 

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D10102 D10102 2-0 PDS PLUS VIOLET 1X36" RB-1 DOUBLE ARMED 

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D9972 D9972 1 PDS PLUS VIOLET 1X96" OS-8 

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D9983 D9983 2-0 PDS PLUS VIOLET 1X27" UR-6 

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PDP114H PDP114H 2-0 PDS PLUS VIOLET 1X27" UCL 

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PDP117H PDP117H 6-0 PDS PLUS VIOLET 1X30" BV-1 DOUBLE ARMED 

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PDP123H PDP123H 6-0 PDS PLUS VIOLET 1X30" BV DOUBLE ARMED 

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PDP126H PDP126H 5-0 PDS PLUS VIOLET 1X30" C-1 DOUBLE ARMED 

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PDP127H PDP127H 6-0 PDS PLUS VIOLET 1X30" C-1 DOUBLE ARMED 

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PDP137H PDP137H 4-0 PDS PLUS VIOLET 1X36" V-5 DOUBLE ARMED 

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PDP148H PDP148H 5-0 PDS PLUS VIOLET 1X30" RB-2 DOUBLE ARMED 

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PDP149H PDP149H 6-0 PDS PLUS VIOLET 1X30" RB-2 DOUBLE ARMED 

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PDP259H PDP259H 2-0 PDS PLUS UNDYED 1X27" CT-1 

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PDP303H PDP303H 5-0 PDS PLUS VIOLET 1X27" RB-1 

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PDP304H PDP304H 4-0 PDS PLUS VIOLET 1X27" RB-1 

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PDP305H PDP305H 3-0 PDS PLUS VIOLET 1X27" RB-1 

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PDP310H PDP310H 4-0 PDS PLUS VIOLET 1X27" SH-1 

References

*21 RCTs, 6462 patients, 95% CI: (14, 40%), P<0.001.

†All triclosan-coated sutures in these RCTs were Ethicon Plus Antibacterial Sutures (MONOCRYL® Plus Antibacterial [poliglecaprone 25] Suture, Coated VICRYL® Plus Antibacterial [polyglactin 910] Suture, and PDS® Plus Antibacterial [polydioxanone] Suture).
 
‡Clean wounds 10 RCTs, 2842 patients, 95% CI: (11-43%), P=0.003; non-clean wounds 14 RCTs, 3620 patients, 95% CI: (7-42%). 

||As shown in coronary artery bypass surgery.

§On average, compared to traditional sutures.

¶Guidelines on reducing the risk of surgical site infections are general to triclosan-coated sutures and are not specific to any one brand.

#In preclinical studies ex vivo model.

**PDS Plus and MONOCRYL Plus sutures only. 

††Staphylococcus aureus, Staphylococcus epidermidis, methicillin-resistant Staphylococcus aureus (MRSA), methicillin-resistant Staphylococcus epidermidis (MRSE), Escherichia coli, and Klebsiella pneumoniae. 

‡‡Refers only to STRATAFIX™ Symmetric PDS™ Plus, STRATAFIX™ Spiral PDS™ Plus, and STRATAFIX™ Spiral Monocryl™ Plus. 

1. PDS® Plus Antibacterial (polydioxanone) Suture Instructions for Use. Ethicon, Inc. 

2. Ming X, Rothenburger S, Nichols MM. In vivo and in vitro antibacterial efficacy of PDS Plus (polidioxanone with triclosan) suture. Surg Infect (Larchmt). 2008;9(4):451-457.

3. de Jonge SW, Atema JJ, Solomkin JS, Boermeester MA. Meta-analysis and trial sequential analysis of triclosan-coated sutures for the prevention of surgical-site infection. Br J Surg. 2017;104(2):e118-e133.

4. Oxford Centre for Evidence-based Medicine. Levels of Evidence. March, 2009. https://www.cebm.net/2009/06/oxford-centre-evidence-based-medicine-levels-evidence-march-2009/. Accessed September 8, 2020. 

5. Plus Suture Cost Analysis. 2019 Ethicon, Inc.

6. de Lissovoy G, Pan F, Patkar A, et al. Surgical Site Infection Incidence and Burden Assessment Using Multi-institutional Real-world Data. Presented at: EU ISPOR Meeting; November 5-8, 2011; Madrid, Spain.

7. World Health Organization Global Guidelines for the Prevention of Surgical Site Infection, 2018. https://apps.who.int/iris/bitstream/handle/10665/277399/9789241550475-eng.pdf. Accessed May 9, 2020.

8. Berríos-Torres SI, Umscheid CA, Bratzler DW, et al. Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017. JAMA Surg. 2017;152(8):784-791. doi:10.1001/jamasurg.2017.0904.

9. Ban KA, Minei JP, Laronga C, et al. American College of Surgeons and Surgical Infection Society: Surgical Site Infection Guidelines, 2016 Update. J Am Coll Surg. 2016;224(1):59-74. 

10. National Institute for Health and Care Excellence (NICE) Guideline. Surgical site infections: prevention and treatment. NICE website. https://www.nice.org.uk/guidance/ng125/chapter/Recommendations#closure-methods. Accessed July 2, 2020. 

11. Prevention of postoperative wound infections. Recommendation of the Committee for Hospital Hygiene and Infection Prevention (KRINKO) at the Robert Koch Institute. Bundesgesundheitsbl. 2018;61(4):448-473.

12. Bhende S, Burkley D, Nawrocki J. In vivo and in vitro anti-bacterial efficacy of absorbable barbed polydioxanone monofilament tissue control device with triclosan. Surg Infect (Larchmt). 2018;19(4):430-437.