PROLENE® Polypropylene Suture with HEMO-SEAL™ Technology

A unique needle-suture combination which helps preserve visualization of the surgical site and enables accurate bite placement by significantly reducing needle hole bleeding.

PROLENE® Polypropylene Suture with HEMO-SEAL™ Technology

Features & Benefits

blood transfusion

Because Every Drop Matters

HEMO-SEAL™ preserves this precious resource. During surgery, bleeding can disrupt a clear surgical field and hinder visualization when you need it most. HEMO-SEAL™  Needle Suture Technology was designed with this in mind – it’s a needle-suture combination that allows a better fit of the suture in the needle hole, resulting in reduced needle hole bleeding

hemoseal tech has reduced needle hole leakage compared to prolene

The PROLENE® You Trust – but Better

Same handling. Reduced leakage. Better visualization. HEMO-SEAL™ Technology uses the same PROLENE® suture you trust, but offers reduced needle hole leakage. In a pre-clinical model, HEMO-SEAL Technology was shown to reduce needle hole leakage rate by 67% compared to the standard PROLENE Polypropylene Suture; and by 59% compared to GORE-TEX® ePTFE Nonabsorbable Monofilament Suture.1†

prolene® polypropylene suture with hemo-seal™ technology

How HEMO-SEAL™ Technology Works

Tapered suture. 1-to-1 needle-to-suture ratio. HEMO-SEAL Technology narrows the PROLENE suture at the needle attachment site, which results in the remainder of the suture having a reduced needle-to-suture ratio. This enhanced ratio allows the bulk of the suture to adequately fill the needle hole, leading to a significant reduction in needle hole bleeding.



How HEMO-SEAL Technology works
How HEMO-SEAL Technology works
PROLENE® Polypropylene Suture with HEMO-SEAL™ Technology vs. Gore-TEX®
PROLENE® Polypropylene Suture with HEMO-SEAL™ Technology vs. Gore-TEX®

Supporting Documentation

Product Support

PROLENE with HEMO-SEAL technology vs GORETEX Brochure


ETHICON Edge Competitive Performance Testing : Needles and Sutures


† A comparative analysis of the suture hole leak rate of Standard 5-0 PROLENE® Polypropylene Suture, 5-0 HEMO-SEAL™ Needle Suture, and 5-0 GORE-TEX® EPTFE non-absorbable monofilament suture following an EPTFE to EPTFE vascular gradt anastomosis in an ex vivo cariopulmonary bypass pulsatile flow loop model with heparinized porcine blood. 
Rosin E, Robinson GM. Knot security of suture materials. Vet Surg. : VS. 1989;18(4):269-273.

1. Miller CM, Sangiolo P, Jacobson JH. Reduced anastomotic bleeding using new sutures with a needle-suture diameter ratio of one. Surgery. 1987; 101(2): 156-160. 

For complete indications, contraindications, warnings, precautions, and adverse reactions, please reference full package insert.