STRATAFIX™ Knotless Tissue Control Devices

STRATAFIX™ is a portfolio of barbed sutures that deliver more efficiency, more strength,* and more consistency than traditional suture.1-3 Use the STRATAFIX™ Selection Guide to help you choose the right STRATAFIX™ for you.

STRATAFIX™ Knotless Tissue Control Devices

Features & Benefits

STRATAFIX barbed sutures close wounds faster than interrupted technique for time savings 
in operating room

More efficiency

STRATAFIX™ barbed sutures can close wounds substantially faster than using an interrupted technique.4 In Total Hip Arthroplasty, STRATAFIX™ was associated with significantly less time spent in the OR when compared to traditional sutures.5†

STRATAFIX barbed sutures demonstrated superior holding strength vs interrupted with coated vicryl or looped pds

More strength

STRATAFIX™ Symmetric Devices provide superior tissue-holding strength compared to interrupted technique with Coated VICRYL® (polyglactin 910) Suture, continuous technique with PDS® II (polydioxanone) Suture, and V-Loc™ 180 Wound Closure Device.3‡§

STRATAFIX barbed suture have barbs that are uniquely designed for a secure hold and consistency

More consistency

With significantly more points of fixation than traditional sutures, STRATAFIX™ makes it easier to manage tension on every pass; appropriate tension leads to better wound healing, a prerequisite for good cosmesis.6,7||

STRATAFIX barbed sutures with plus technology have triclosan for reduced risk of surgical site infection

More protection

STRATAFIX™ Plus Knotless Tissue Control Devices have been shown in vitro to inhibit bacterial colonization of the suture for 11 days or more,9**††‡‡ for protection against the most common organisms associated with SSI.9§§||||

References

*Refers to STRATAFIX™ Symmetric PDS™ Plus Knotless Tissue Control Device only.

†Based on retrospective analysis of 5,958 cases from the Premier Perspective® Hospital Database.

‡In an ex vivo model.

§Superior to VICRYL and PDS in fascia. Superior to V-Loc in subcutaneous tissue.

||Conclusions of suture tension and outcomes based on animal model.

¶In a meta-analysis of 21 Randomized Controlled Trials (RCTs), 6462 patients, 95% CI: (14, 40%), P<0.001.
 
#All triclosan-coated sutures in these RCTs were Ethicon Plus Antibacterial Sutures (MONOCRYL® Plus Antibacterial [poliglecaprone 25] Suture, Coated VICRYL® Plus Antibacterial [polyglactin 910] Suture, and PDS® Plus Antibacterial [polydioxanone] Suture).

**Meta-analysis only included traditional (nonbarbed) sutures.

††In vivo.

‡‡In vitro.

§§Staphylococcus aureus, Staphylococcus epidermidis, Methicillin-resistant S. aureus (MRSA), Methicillin-resistant S. epidermidis (MRSE), Escherichia coli, Klebsiella pneumoniae.

||||Refers only to STRATAFIX™ Symmetric PDS™ Plus, STRATAFIX™ Spiral PDS™ Plus and STRATAFIX™ Spiral MONOCRYL™ Plus.

1. Moran ME, Marsh C, Perrotti M. Bidirectional-barbed sutured knotless running anastomosis v classic Van Velthoven suturing in a model system. J Endourol. 2007;21(10):1175-1178. 

2. Vakil JJ, O'Reilly MP, Sutter EG, Mears SC, Belkoff SM, Khanuja HS. Knee arthrotomy repair with a continuous barbed suture: a biomechanical study. J Arthroplasty. 2011;26(5):710-713. 

3. Nawrocki J. Time zero tissue holding - competitive claims comparisons for STRATAFIX Knotless Tissue Control Devices vs various products. 100326296. May 20, 2015. Ethicon, Inc.  

4. Greenberg J, Goldman R. Barbed suture: a review of the technology and clinical uses in obstetrics and gynecology. Rev Obstet Gynecol. 2013;6(3-4):107-115.

5. Sutton N, Schmitz ND, Johnston SS. Comparing outcomes between barbed and conventional sutures in patients undergoing knee or hip arthroplasty. J Comp Eff Res. 2018;7(10):975-987. doi:10.2217/cer-2018-0047.

6. Burgess LP, Morin GV, Rand M, Vossoughi J, Hollinger JO. Wound healing. Relationship of wound closing tension to scar width in rats. Arch Otolaryngol Head Neck Surg. 1990;116(7):798-802.

7. Höer J, Klinge U, Schachtrupp A, Töns C, Schumpelick V. Influence of suture technique on laparotomy wound healing: an experimental study in the rat. Langenbecks Arch Surg. 2001;386(3):218-223.

8. de Jonge SW, Atema JJ, Solomkin JS, Boermeester MA. Meta-analysis and trial sequential analysis of triclosan-coated sutures for the prevention of surgical-site infection. Br J Surg. 2017;104(2):e118-e133. doi:10.1002/bjs.10445.

9. Bhende S, Burkley D, Nawrocki J. In vivo and in vitro antibacterial efficacy of absorbable barbed polydioxanone monofilament tissue control device with triclosan. Surg Infect (Larchmt) 2018;19(4):430-437.