VISTASEAL™ Fibrin Sealant (Human)

VISTASEAL mimics the clot formation process and forms a rapid, adherent, and durable clot regardless of the patient’s coagulation profile1,2

VISTASEAL Fibrin Sealant Now Available

Features & Benefits

vistaseal provides sustained hemostasis brochure

Provides sustained hemostasis

VISTASEAL has been demonstrated to sustain hemostasis even in high-risk patients (friable tissues, anticoagulants, antiplatelets, and coagulopathies)2,3,4

vistaseal no other fibrin sealant preps faster video

No other fibrin sealant preps faster5*

In addition to providing a reliable fibrin clot independent of the patient’s coagulation profile, VISTASEAL offers more. With click-on dual applicator, airless spray design, and no additional warming needed after thawing1, VISTASEAL enables faster preparation than any other fibrin sealant on the market.

vistaseal offers enhanced control for exceptional performance-spray comparison

VISTASEAL offers enhanced control for exceptional performance

VISTASEAL improves user experience for the entire surgical team, with flexibility to spray in a narrow or broad pattern with a single device, malleable spray tip for access to challenging anatomy, and broad working temperature.1

vistaseal use open and laparoscopic procedures order now

Use it in open and laparoscopic procedures

And enjoy more flexibility – whether ordered individually or by the kit, VISTASEAL is shipped quickly and sent in environmentally friendly packaging. 


Product Code

Product Code


VST10 VST10 VISTASEAL Fibrin Sealant (Human), 10 mL 

Product Code

Product Code


04VST10 04VST10 VISTASEAL Fibrin Sealant (Human) 10 mL–4 pack Kit 

Product Code

Product Code


12VST10 12VST10 VISTASEAL Fibrin Sealant (Human) 10 mL–12 pack Kit 

Product Code

Product Code


VSTL35 VSTL35 VISTASEAL Laparoscopic Dual Applicator 35 cm Rigid 

Product Code

Product Code


VSTL45 VSTL45 VISTASEAL Laparoscopic Dual Applicator 45 cm Flexible 


VISTASEAL™ Fibrin Sealant (Human)
VISTASEAL Product Overview Video
VISTASEAL vs TISSEEL Open Spray Comparison
VISTASEAL Variable Spray
VISTASEAL Traditional Drip vs. Focused Spray
VISTASEAL Laparoscopic Tip Handling (Trocar)
VISTASEAL Assembly Comparison - Frozen
VISTASEAL Assembly Comparison - Thawed

Supporting Documentation

Product Support

VISTASEAL Ordering Fact Sheet

VISTASEAL Optimized Device Performance Quick Guide



*Based on number of set-up steps and thawing time required for VISTASEAL™ Dual Applicator vs competitors.

1. VISTASEAL™ Fibrin Sealant (Human). Full Prescribing Information. Instituto Grifols, S.A. 2019.

2. Bjelovic M, Ayguasonosa J, Kim RD, et al. A prospective, randomized, phase III study to evaluate the efficacy and safety of fibrin sealant Grifols as an adjunct to hemostasis as compared to cellulose sheets in hepatic surgery resections. J Gastrointest Surg. 2018. 22:1939-1949. 

3. Chetter I, Stansby G, Sarralde JA, et al. A prospective, randomized, multicenter clinical trial on the safety and efficacy of a ready-to-use fibrin sealant as an adjunct to hemostasis during vascular surgery. Ann Vasc Surg. 2017;45:127-137.

4. Hunt BJ. Bleeding and coagulopathies in critical care. N Engl J Med. 2014;370:847-859.

5. Thawing time and set-up steps comparison between VISTASEAL, EVICEL, and TISSEEL. Report 100708726-Rev 2. August 28, 2019. Ethicon, Inc.



VISTASEAL™ is indicated as an adjunct to hemostasis for mild to moderate bleeding in adults undergoing surgery when control of bleeding by standard surgical techniques (such as suture, ligature, and cautery) is ineffective or impractical.  VISTASEAL is effective in heparinized patients.

Do not inject directly into the circulatory system. 
Do not use for the treatment of severe or brisk arterial bleeding.
Do not use in patients with history of anaphylaxis or severe systemic reactions to human blood products.
Do not use VISTASEAL for spraying unless the minimum recommended distance from the applicator tip to the bleeding site can be achieved. 

Thromboembolic events may occur if VISTASEAL is administered intravascularly. 
Only spray VISTASEAL if it is possible to accurately judge the distance from the spray tip to the tissue surface. 
Hypersensitivity reactions can occur. 
May carry a risk of transmitting infectious agents, e.g., viruses, the variant Creutzfeldt-Jakob disease (vCJD) agent and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent. 

The most common adverse reactions (reported in >1% of clinical trial subjects) were nausea and procedural pain. 
For complete indications, contraindications, warnings, precautions, and adverse reactions, please reference full package insert.